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FDA Approves Onglyza for Type 2 Diabetes

Bristol-Myers Squibb and AstraZeneca received FDA approval for Onglyza as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.

Bristol-Myers Squibb and AstraZeneca received FDA approval for Onglyza as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. Onglyza is a once-daily dipeptidyl peptidase-4 (DPP4) inhibitor that can be used in combination with commonly prescribed anti-diabetic medications or as a monotherapy to significantly reduce glycosylated hemoglobin (A1C) levels.

“The FDA approval of Onglyza is an important development for adult patients with type 2 diabetes struggling every day to control their blood sugar levels. Nearly half of adult patients remain uncontrolled on their current treatment regimen and may thus require additional medications,” said Elliott Sigal, M.D., Ph.D., executive vice president, chief scientific officer, and president, R&D, BMS. “Our ongoing clinical trial program has demonstrated that Onglyza showed improved A1C control both in combination and monotherapy settings.”


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